Blar i forfatter "Aljabri, Mohammad Belal"

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    • Angiotensin II and heart remodelling : role of ischemia, gender and pregnancy 

      Aljabri, Mohammad Belal (Doctoral thesis; Doktorgradsavhandling, 2011-05-26)
      In this thesis different factors that promote or inhibit heart remodelling induced by angiotensin II were studied. The following conclusions can be drawn: 1. The presence of elevated levels of Ang II in the perfusion buffer did not increase myocardial injury during ischemia-reperfusion. However, the ability to protect the heart by ischemic postconditioning was lost. This seemed to be due to ...

    • Downstream gene expression of wild type p53 tumor suppressor gene versus mutated and null p53 

      Aljabri, Mohammad Belal (Master thesis; Mastergradsoppgave, 2006-11)
      P53 is a key tumor suppressor and transcription factor protecting us from cancer. The wild type p53 protein functions as a regulatory protein, triggering a variety of cellular responses to different signals. Activation of p53 can lead to cell division arrest, DNA repair, or apoptosis. More than 60% of all human cancers contain p53 mutations. P53 is also reported in many studies to play a role in the ...

    • Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of Angiotensin II 

      Aljabri, Mohammad Belal; Lund, Trine; Høper, Anje Christina; Andreasen, Thomas Vennø; Al-Saad, Samer; Lindal, Sigurd; Ytrehus, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)

    • Gene Expression, Function and Ischemia Tolerance in Male and Female Rat Hearts After Sub-Toxic Levels of Angiotensin II 

      Aljabri, Mohammad Belal; Lund, trine; Høper, Anje Christina; Andreasen, thomas vennØ; Al-Saad, Samer; Lindal, Sigurd; Ytrehus, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2010-12-19)
      To examine the response to chronic high-dose angiotensin II (Ang II) and a proposed milder response in female hearts with respect to gene expression and ischemic injury. Female and male litter–matched rats were treated with 400 ng kg<sup>-1</sup> min<sup>-1</sup> Ang II for 14 days. Hearts were isolated, subjected to 30-min ischemia and 30-min reperfusion in combination with functional monitoring ...